Jordan Larmour has been ruled out of Ireland's entire autumn campaign.
His province Leinster confirmed on Monday that the full-back suffered a dislocated shoulder in Saturday's Guinness PRO14 win away to Benetton.
Larmour will undergo a procedure this week to rectify the issue, but will miss the remaining Six Nations games with Italy and France plus the Autumn Nations Cup.
The 23-year old was administered oxygen as he left the field early in the second half of Leinster's 37-25 bonus point win in Treviso. He was replaced in the game by Jimmy O'Brien.
No timeline has been placed on Larmour's recovery.
Doubt continues to hover over one of the new Ireland call-ups, Ryan Baird.
The up-and-coming lock was replaced with 16-minutes to go of the game in Italy with Leinster saying he suffered an adductor strain. Baird will be assessed this week ahead of the PRO14 meeting with Zebre at the RDS.
Leinster head coach Leo Cullen confirmed that Max Deegan sustained an ACL knee injury in the opening weekend win over the Dragons and the no.8 will be "unavailable for a number of months".
Jonathan Sexton and Andrew Porter's respective hamstring injuries, and Ronan Kelleher's quad problem, will all be attended to this week by the IRFU medical team.
Tadhg Furlong is continuing to rehab his calf injury and will continue to work with Leinster's strength and conditioning and medical teams this week.